Background: When post-op radiation therapy is planned, closure of large wounds with reliable vascularized cutaneous flaps is preferable to soft tissue flaps covered by STSG. In combining the vascular territories of the medial and lateral descending branches of the Lateral Femoral Circumflex artery we describe a novel flap that serves to provide quality cutaneous coverage for large soft tissue defects on a single arterial pedicle. Methods: A 45 x 30 cm near circumferential perforator thigh flap was successfully transferred to a large shoulder defect with a single arterial (LFC) anastomosis and two venous (LFC and Saphenous) anastomoses. The entire flap was perfused by perforators of the medial and lateral branches of the LFC system, as well as muscular perforators arising via the incorporated rectus femoris muscle. Results: There were no flap related complications, nor were there donor site complications during the patient's post-op recovery. Conclusions: This near circumferential perforator thigh flap provides an additional option to reconstruct truly giant defects with a relatively thin skin flap, in lieu of combination flaps or soft tissue flaps covered by skin grafts. Morbidity is minimized by using donor tissues from a single location that, when harvested, result in a negligible functional impairment.