Marjolin's Ulcer is a rare malignant lesion arising from wounds of a chronic nature. Predominantly associated with burns, this malignant degeneration can occur less frequently in other types of wounds. This is a case report of a 52 year old man paraplegic for 38 years who presented to a local plastic surgeon with a long standing, non-healing pressure sore. Only after biopsy of the wound was it found to be a squamous cell carcinoma with metastases to the groin. As plastic surgeons, we are routinely consulted for chronic, non-healing wounds. We must remain vigilant and aware that these wounds can progress to life threatening condition.