Medial thigh lift combined with liposuction is a safe procedure resulting in significant patient satisfaction. There is limited literature available focusing on the prevention of intraoperative complications. The greater saphenous vein (GSV) is prone to injury as it courses near the target of suction lipectomy and medial thigh lift flap dissection. Despite this, preoperative studies to evaluate GSV location are rarely performed due to significant expense and limited logistical support. A simple, safe and inexpensive technique is described to assess the location of GSV using intraoperative duplex ultrasound. This technique was performed in a patient undergoing bilateral thigh liposuction and medial thigh lift utilizing two-dimensional ultrasound equipment. The intraoperative ultrasound was performed by the plastic surgeon and completed in less than 5 minutes. The operative findings correlated with ultrasound findings and allowed easy avoidance of the GSV during elevation of the thigh flap. Intraoperative GSV duplex scanning is rapidly and easily accomplished with already available operating room resources. Intraoperative venous duplex ultrasound scanning provides knowledge of the GSV location which expedites surgical dissection throughout the procedure.