Purpose: Integra dermal regeneration template has been associated with hyperpigmentation of the healed wound.

Method(s): A retrospective review of wounds treated with Integra neodermis in the senior author's practice over the last five years was performed. All cases were directly observed the senior surgeon. Results were confirmed by review of photographs. Wound pigmentation was rated as excellent, good, fair, or poor. Pigmentation outcomes were compared to the native skin types to determine whether different skin types had more or less favorable pigment outcomes.

Results/Objectives: There was a high association of wound hyperpigmentation and darker skin types. Patients with lighter skin types obtained excellent or good color match in the majority of cases.

Conclusions: Integra dermal regeneration template produces excellent or good skin color match in the majority of lighter skin type patients. Hyperpigmentation occurs frequently in darker skin type patients.