“Vacuum Assisted Closure”(VAC) had dramatically changed the approach to the management of wounds. After we realized that some patients were not willing to continue prosedure we decided to investigate anxiety level of these patients.  The aim of this study was to verify the possibility of different anxiety levels in individuals in whom the VAC device was applied. Psychological evaluations were done on subjects on the day before VAC application and 10^th day of the treatment in 10 patients with extremity wounds. Anxiety was measured with the Hamilton Rating Scale for Anxiety(HAM) and with the State Anxiety Inventory(SAI) tests. Same measurements were also done in 10 patients with similar wounds but managed with classical therapies for comparison. Both groups showed a significant increase in anxiety levels, however when the increase percentage of two groups for both tests were compared, the increases were significant in the VAC group.(Table) Although the VAC therapy is very effective in treating lower extremity wounds, concerns should be given for possible accompanying psychological side effects.  

	Control groups	VAC groups	p
SAI	4.53±5.65	30.24±27.02	0.004
HAM	16.70±15.15	80.12±79.48	0.002

Table. Comparison of the control and VAC groups regard to both percentage differences(D%) of mean SAI and HAM scores.